Light Yagami's patient, layered manipulation outpaces every deduction Sherlock makes, delivering the name and face he needs to bring the Death Note down as the decisive, unanswerable blow.
Namor's superhuman physicality and three-tier power advantage gave Holmes no viable path to end the fight, while Namor's superior speed and kill-capable strength closed the gap before Holmes's genius could compensate.
Ironheart's energy-based weapons and superior speed let her strike Sherlock Holmes from range where his purely human defenses cannot respond, and she holds a clear path to end the fight that he has no means to counter.
Agent Smith's far greater speed and strength let him land a decisive blow that Sherlock Holmes, a human with fragile physical limits, cannot recover from.
T-1000 wins because its super speed keeps it ahead of Sherlock Holmes at every exchange, and its regeneration and shape shifting let it recover from each blow Holmes lands, until a decisive finishing strike ends the fight.
Vegito's multiversal-scale speed and energy output instantly overwhelm a baseline human detective with no superhuman durability or defensive abilities.
Wizards, dark lords and things that live in the woods.
Xenomorphs, terminators and the far future.
Slashers, entities and whatever is behind you.
Toon logic and the rules it refuses to follow.
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