Anos Voldigoad's reality-warping dismantles Rimuru's regeneration at its foundation, and Venuzdonoa delivers a blow that cuts beneath every defense Rimuru possesses, leaving him with nothing to get up from.
Goku is far faster than Rimuru, dodging and countering on instinct, so he lands the decisive Kamehameha that Rimuru cannot get up from.
Sukuna's domain keeps delivering its lethal cutting payload across the whole fight, so Muzan's regeneration can never keep up with the damage until it is finished.
Muzan Kibutsuji wins because his instantaneous regeneration makes every Sun Breathing technique Yoriichi lands survivable, while a single decisive strike against Yoriichi's human body is all Muzan needs to end the fight permanently.
Deku's combination of superior speed in critical moments and tactical expertise allowed him to identify and exploit All Might's vulnerability immediately after All Might's finishing technique committed, delivering a Delaware Smash that All Might could not rec…
Goku's far superior speed lets his body dodge and counter Giorno before any finishing blow connects, and his Kamehameha delivers the decisive knockout Giorno cannot recover from.
Dragon Ball
Saiyans, gods of destruction and the ones above them.
One Piece
Devil fruits, haki and the Grand Line.
Jujutsu Kaisen
Cursed energy, domains and the ones who bend them.
Naruto
Chakra, tailed beasts and the Sage of Six Paths.
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